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Alexander Katiraie

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Men with 'beer bellies' may face serious heart damage regardless of weight

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New study reveals "beer bellies" increase heart damage risk even in people with normal weight, challenging traditional views on cardiovascular health.

Published: December 1, 2025, 8:02 pm

New cancer therapy hunts and destroys deadly tumors in major breakthrough study

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Researchers at UCLA have created an “off-the-shelf" cell-based immunotherapy that can seek out and destroy pancreatic cancer cells, even after the cancer has spread to other organs.

Published: December 1, 2025, 12:00 pm

Is it true that … a glass of wine a day is good for your heart?

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Moderate wine consumption may benefit your cardiac health, but foods such as grapes and berries offer similar advantages without the negative effects

“People shouldn’t think that drinking wine is good for you,” says Dr Oliver Guttmann, a consultant cardiologist at the Wellington hospital in London.

Alcohol consumption is linked to high blood pressure, liver disease, digestive, mental health and immune system problems, as well as cancer.

Continue reading...

Published: December 1, 2025, 8:00 am

UK energy suppliers’ customer service: a tragedy (and a farce) in three acts

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Weird tales of meter mix-ups, incomprehensible bills, and to foment the drama, a teenager threatened with a trashed credit rating

On a dark winter’s night, what could be more engrossing than my latest tragifarce about energy firms, guaranteed to set spines tingling?

Continue reading...

Published: December 1, 2025, 7:00 am

After Trump’s M.R.I. Claim, His Doctor’s Memo Offers Little Clarity

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While the president said he had a M.R.I. exam, a physician’s memo released by the White House was less specific.

Published: December 2, 2025, 3:45 am

Female Cardiothoracic Surgeons, Unlocking the Male Fortress

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Less than 10 percent of heart and lung surgeons in the United States are women. At a recent conference, they vowed to change that.

Published: December 1, 2025, 8:45 pm

A Different Type of Dementia Is Changing What’s Known About Cognitive Decline

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On its own, LATE dementia is less severe than Alzheimer’s, but in combination, it makes Alzheimer’s symptoms worse, scientists say.

Published: December 1, 2025, 1:38 pm

Solving the Home Care Quandary

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Paid home care is buckling under the surging demands of an aging population. But there are alternatives that could upgrade jobs and improve patient care.

Published: December 2, 2025, 8:00 am

James Riches, Fire Chief Who Lost Firefighter Son on 9/11, Dies at 74

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He spent months searching the wreckage of the World Trade Center for his son’s remains, then suffered lung illnesses attributed to toxic dust.

Published: December 2, 2025, 4:30 am

The Autism Diagnosis Problem

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Autism rates have increased in recent decades, but the reasons are more complicated than what Robert F. Kennedy Jr. has presented.

Published: December 1, 2025, 8:51 am

Is this the END of Ozempic? Inside secret food industry plan to keep people eating even while taking weight-loss drugs… and the beloved American brands involved

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In a new book, Off the Scales: The Inside Story of Ozempic and the Race to Cure Obesity, author Aimee Donnellan describes how Big Food giants are grappling with a post-semaglutide reality.

Published: December 1, 2025, 8:03 pm

Huge Alzheimer's breakthrough as weight-loss jab already prescribed to thousands on the NHS is found to slow progression of memory-robbing illness

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Liraglutide - sold under the brand name Saxenda - is often offered to people with with a BMI of over 30 as it improves blood sugar control and aids weight loss.

Published: December 1, 2025, 7:42 pm

The strike-mare before Christmas: Doctors union throws NHS into chaos after announcing ANOTHER five day walkout

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British Medical Association bosses claimed they had 'no choice but to announce more strike dates' after the Government failed to put forward a 'credible plan'.

Published: December 1, 2025, 6:52 pm

Diet experts rank 91 high street Christmas sandwiches: They found a panini saltier than 12 packets of crisps and a wrap with more sugar than two doughnuts - so how bad is YOUR favourite?

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The 91 sandwiches on offer this year from 14 supermarkets and shops include Christmas dinner stuffed between slices of bread and even a sweet mince pie wrap.

Published: December 1, 2025, 6:23 pm

Before, with or after meals? Why medications timing matters

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Many medications can be taken before, after or during a meal with little to no side effects-but for some, timing is everything.

Published: December 1, 2025, 4:57 pm

The single injection that means you could come off statins for LIFE: Experts hail 'fabulous' breakthrough that permanently cuts cholesterol... and may mean an end to difficult statin side-effects

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A one-off shot of a new drug could cut high cholesterol levels for life. The 'game-changing' drug works by switching off a gene involved in the production of so-called 'bad' cholesterol - or LDL.

Published: December 1, 2025, 4:55 pm

Smelling bacon in the WOMB could be cause of adulthood obesity, scientists suggest

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German researchers have suggested that the smell of such fatty foods increases the risk of babies developing the condition later in life.

Published: December 1, 2025, 4:48 pm

Two weeks after our honeymoon, my super-fit rugby player husband was given five years to live... people think we're selfish, but his brain tumour won't stop us from starting a family

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Returning from their idyllic honeymoon, newlyweds Vicky and Tom Chapman couldn't wait to start trying for a baby-blissfully unaware of the bombshell health news awaiting them.

Published: December 1, 2025, 4:21 pm

I was the Daily Mail's health editor and covered the mysterious surge in cancer in young people. But at just 29, there was an aggressive tumor inside me… even I missed these hidden signs

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The panic hit first. Then came the embarrassment. After all, I'd spent years giving health advice to colleagues, friends and family, convinced I was an expert in many areas of medicine.

Published: December 1, 2025, 4:16 pm

Urgent health warning is issued over a very disturbing side-effect linked to trendy new weight loss drugs like Ozempic and Mounjaro

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The Therapeutic Goods Administration issued a new warning for GLP-1 receptor agonists on Monday.

Published: December 1, 2025, 1:47 pm

Worrying side-effect of creatine you aren't being warned about: Cheap supplement is hailed as a 'miracle' - but here's how to tell if YOUR brand is doing more harm than good

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A cheap powder loved by bodybuilders has surprising benefits for women in perimenopause and beyond - but what about the downsides?

Published: December 1, 2025, 1:36 pm

NHS surgeon urges public not to ignore key symptoms of deadly prostate cancer: 'It kills one man every 45 minutes'

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It's one of the most common forms of cancer in men, yet too many do not know the crucial warning signs to look out for, a leading cancer surgeon has warned.

Published: December 1, 2025, 12:45 pm

I feel constantly nauseous, can't eat and have lost a stone. DR SCURR reveals the terrifying silent conditions behind sudden weight loss - and how you can cure them

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A reader asks: After having Covid I went off food because of nausea. I'm still hardly eating and have lost a stone.

Published: December 1, 2025, 11:45 am

Man, 30, opens up on the hell of living with condition that causes him to vomit 60 times a DAY - and claims local NHS refused to fund £15k 'life-changing' device

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A man who vomits up to 60 times a day was forced to buy a new £15,000 battery for a 'life-changing' device that helps control his condition-after local NHS chiefs refused.

Published: December 1, 2025, 9:44 am

Expert shares seven tips for surviving the chaos of Christmas season if you're living with ADHD or autism

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It's a stressful time of year for people living with autism and ADHD says Dr Selina Warlow a psychologist and founder of The Nook Clinic, but there are ways to get through it.

Published: December 1, 2025, 9:16 am

Obese man who weighs 23 stone claims NHS won't give him second round of weight loss surgery... because he has ADHD

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A severely obese man has allegedly been refused weight loss surgery on the NHS because of his attention deficit disorder, despite suffering a number of weight-related conditions.

Published: December 1, 2025, 8:43 am

Woman, 30, devastated after 'lactose intolerance' turns out to be symptom of incurable bladder cancer

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A woman was told by doctors that her stomach problems were likely due to food intolerances and irritable bowel syndrome, but they were actually symptoms of an incurable type of cancer .

Published: December 2, 2025, 7:00 am

Thinking about weight-loss jabs but fear the side effects? Try these miracle foods dubbed 'nature's Ozempic' that produce GLP-1 BEFORE you book that telehealth appointment

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'What if I told you that you can introduce foods into your diet that help the body increase its natural production of GLP-1? Foods you can enjoy that have no side effects ...'

Published: December 2, 2025, 5:23 am

NHS emergency care crisis laid bare: 2025 set to be worst year on record damning figures show, as Labour is accused of being in 'total denial'

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Over 452,000 people waited 12 hours or more for a bed from January to October after medics decided they were so sick they needed to be admitted to a ward.

Published: December 2, 2025, 2:33 am

The two food mistakes millions make that increase their risk of chronic disease

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Millions of Americans are unknowingly making simple food choices that doctors warn are silently raising their risk of cancer , heart disease and diabetes.

Published: December 2, 2025, 2:17 am

A simple prescription taken by 1 million Americans made my skin blister from head to toe - and my organs fail. Doctors say I'm the sickest patient that's ever lived

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Christine Sentz's ordeal began with a simple prescription, but quickly escalated into a near-death medical crisis. 

Published: December 2, 2025, 1:57 am

How you can learn to control your dreams... and change your life. Doctors now say 'lucid dreaming' techniques can treat phobias, insomnia and even depression - and reveal the cheap supplements that can help you do it

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Throughout his late teens and early 20s, Matthew Humphreys was prone to low moods. He ignored them until, in his mid-20s, the negative thoughts and feelings of emptiness became more pronounced.

Published: December 2, 2025, 1:13 am

A GP told us Lyla had tonsillitis and to take her to hospital if she didn't improve. 16 hours later, she was dead from undiagnosed diabetes. These are the warning signs doctors say every parent must know

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Lyla Story was laughing excitedly as she and her older brother fed the animals at a local farm on her second birthday in April.

Published: December 2, 2025, 1:11 am

I had rosacea, IBS, bloating and took a cocktail of pills, says longevity expert DR LARA HEMERYCK. Then I discovered the simple tricks and supplements that have cut my biological age and healed my body. You can do the same

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My health was in dire straits and, aged just 27, I was living a half-life. Profound migraines left me trapped in my bed for days. I had terrible irritable bowel syndrome (IBS).

Published: December 2, 2025, 1:10 am

Thanks to the NHS culture of cover-up and bosses who are rarely held responsible, it took this whistleblower surgeon 16 YEARS to oust a rogue medic at his hospital. How CAN you be sure your doctor won't put you at risk?

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When Michael Swinn blew the whistle on a colleague whose work was endangering lives, he thought the evidence so strong that the trust would promptly tackle the problem.

Published: December 2, 2025, 1:09 am

Colon cancer started wiping out my family... then a little-known test revealed EXACTLY how likely I am to get it too. There are millions like me - but most don't know it. Here's what to ask a doctor

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When Tiffany Graham Charkosky lost her mother to colon cancer 30 years ago, her family thought it was a terrible case of bad luck.

Published: December 2, 2025, 12:22 am

Daily Mail tests the newest 'maxxing' health trend... latest offering only has three ingredients but contains more than 100 grams of protein

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Sweetgreen has launched its new Power Max Protein Bowl, which contains 106 grams of protein. The Daily Mail health team put the bowl to the test, while experts weighed in on the protein content.

Published: December 1, 2025, 10:02 pm

Common breakfast juice boosts heart health and longevity, study finds

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A glass of a common breakfast juice every day could be the key to living longer and boosting heart health, a recent study published by researchers in Brazil and California has suggested.

Published: December 1, 2025, 8:58 pm

Having a 'beer belly' increases risk for deadly diseases more than overall body weight, study suggests

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A high waist-to-hip ratio is a stronger predictor than overall obesity, and German radiologists have linked it to structural changes to the heart.

Published: December 1, 2025, 8:53 pm

Milk recall announced across America as major brand fears it contains cleaning ingredients

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A midwestern dairy plant issued a milk recall after routine testing detected the presence of food-grade cleaning agents in product samples, which can cause illness if ingested.

Published: December 1, 2025, 8:50 pm

More marijuana users being hospitalized for 'scromiting,' doctors warn

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Doctors are warning over a condition that can leave cannabis users screaming in pain and vomiting at the same time.

Published: December 1, 2025, 8:40 pm

Mother-of-one, 43, spurred on to shed seven stone after looking 'fatter than Santa' in grotto photo

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A mother-of-one lost 7st with the help of blockbuster weight loss jab Ozempic, after a Christmas photo left her looking 'fatter than Santa.'

Published: December 1, 2025, 8:30 pm

Stricter guidelines demanded for flu shots by FDA regulator after memo links Covid jabs to deaths of ten kids

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An internal FDA memo said the deaths of at least 10 children were linked to COVID-19 vaccines, which has prompted the agency to demand stricter guidelines for annual flu shots and other vaccines.

Published: December 1, 2025, 7:35 pm

Lori was diagnosed with terminal breast cancer and given two years to live. Now, 20 years later, she is healthy and thriving. This is how she and eight others were 'cured'... and why thousands more could get the same treatment

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Lori Lober is a busy woman. Her Facebook shows a life spent watching American football with her girlfriends and going out for dinner in Kansas City, Missouri, with her husband John.

Published: December 1, 2025, 4:56 pm

The advent calendar of the future? I tried lab-grown CHOCOLATE - and I'd challenge the top chocolatiers to be able to tell the difference between the real-deal!

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California Cultured is one company developing sustainable chocolate - by growing it in the lab from harvested cocoa cells.

Published: December 2, 2025, 8:00 am

The best time to break up with your partner before Christmas, according to experts - and you'd better act quickly

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If you're looking to end an unhappy relationship ahead of the festive season, now's the time to act. 

Published: December 1, 2025, 7:35 pm

Human washing machine that can clean head to toe goes on sale for £290,000 - so, would you give the automatic spa pod a go?

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A 'human washing machine' that can clean a person from head to toe has gone on sale in Japan, but it costs £290,000 (60 million Japanese yen).

Published: December 1, 2025, 3:44 pm

Our tech reporter has scrolled endlessly on Amazon for the best Cyber Monday deals on iPads, laptops, headphones and more

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Get ready to unlock unmissable savings on must-have tech during Cyber Monday, with deals to be had across a huge array of the site's devices.

Published: December 1, 2025, 1:47 pm

Runny nose and itchy eyes? Your Christmas tree could be to blame, expert warns - and fake versions are just as bad

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They bring a touch of cheer into any home - but your Christmas tree could also be triggering a runny nose, sneezing, coughing and itchy eyes, an expert has warned.

Published: December 1, 2025, 12:37 pm

From 'dinosaur tartare' to seaweed butter - would you try any of these dishes created by the world's first AI chef?

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At WooHoo in Dubai, the eccentric menu has been crafted by an AI known as Chef Aiman. But would you be brave enough to try this computer's cooking?

Published: December 1, 2025, 11:13 am

Netflix quietly makes major change to platform with no warning as fans rage over 'customer hostile' policy

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Streaming service Netflix has quietly made a major change which affects all users who watch shows on their phones.

Published: December 1, 2025, 10:37 pm

Urgent warning to Cyber Monday shoppers over scam stealing bank details

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Amazon has warned its customers about a hoax designed to trick shoppers into handing over logins and other personal information.

Published: December 1, 2025, 9:30 pm

Trapped by the swipe? Dating apps are designed to keep singles 'swiping and spending' rather than finding 'The One', experts warn

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A new BBC Three documentary reveals how users are addicted to apps such as Tinder, Hinge and OKCupid in a desperate quest to find 'the one'.

Published: December 1, 2025, 8:25 pm

Record cold for 235 million Americans starting in just HOURS as polar vortex brings 'most extreme cold on Earth'

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Weather officials have warned that more than half the US could see week-long frigid conditions and snow that shatters records for early December.

Published: December 1, 2025, 6:48 pm

Species in Chernobyl disaster zone is mutating to feed on nuclear radiation

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A unique species living at the Chernobyl nuclear disaster site has evolved to have a special ability which could help humans protect themselves against radiation and even cancer.

Published: December 1, 2025, 6:39 pm

Eating two handfuls of a common snack daily improves memory in just four months

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Scientists have discovered that eating just two handfuls of a common snack daily may boost memory and brain blood flow.

Published: December 1, 2025, 6:27 pm

Are you a 'quiet quitter'? You might be a PSYCHOPATH, scientists say

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Psychologists have discovered a strong connection between 'quiet quitting' and so-called 'dark triad' personality traits, including psychopathy and narcissism.

Published: December 1, 2025, 4:08 pm

Pot Bull Terrier! CBD supplements can make dogs less AGGRESSIVE, study finds

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When given to dogs, CBD appears to have a 'calming' effect and 'a decline in the intensity of aggressive behaviours', reveal scientists in the US.

Published: December 1, 2025, 10:32 am

Real Apple support emails used in new phishing scam

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Scammers nearly stole an Apple account by exploiting the support system with authentic-looking tickets and phone calls, users can protect themselves with safety steps.

Published: December 1, 2025, 5:27 pm

Company restores AI teddy bear sales after safety scare

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FoloToy restored sales of its AI teddy bear Kumma after a weeklong suspension following safety group findings of risky and inappropriate responses to children.

Published: December 1, 2025, 11:17 am

Russian Launch Site Mishap Leaves Country’s Space Program in Limbo

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The ability of Russia to launch astronauts to the International Space Station remains in limbo after an incident last week at the Baikonur base in Kazakhstan.

Published: December 1, 2025, 9:06 pm

Inside the Bird-Flu Vaccine Trial for Monk Seals

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After the virus returned to Hawaii this fall, testing the shots in the endangered seal species became urgent.

Published: December 1, 2025, 10:30 am

Solving the Home Care Quandary

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Paid home care is buckling under the surging demands of an aging population. But there are alternatives that could upgrade jobs and improve patient care.

Published: December 2, 2025, 8:00 am

It’s No Dodo, But This Newly Discovered Bird Could Share the Same Fate

The slaty-masked tinamou, found in Brazil, is utterly unafraid of people. That could be its undoing, ornithologists worry.

Published: December 2, 2025, 5:01 am

After Trump’s M.R.I. Claim, His Doctor’s Memo Offers Little Clarity

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While the president said he had a M.R.I. exam, a physician’s memo released by the White House was less specific.

Published: December 2, 2025, 3:45 am

FEMA Won’t Reinstate Suspended Workers Who Signed Letter Criticizing Trump

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Employees suspended in the summer after signing a letter critical of the president were told they could return to work. But the reinstatement was short-lived.

Published: December 1, 2025, 9:54 pm

Many Fighting Climate Change Worry They Are Losing the Information War

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Shifting politics, intensive lobbying and surging disinformation online have undermined international efforts to respond to the threat.

Published: December 1, 2025, 1:27 pm

Female Cardiothoracic Surgeons, Unlocking the Male Fortress

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Less than 10 percent of heart and lung surgeons in the United States are women. At a recent conference, they vowed to change that.

Published: December 1, 2025, 8:45 pm

A Different Type of Dementia Is Changing What’s Known About Cognitive Decline

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On its own, LATE dementia is less severe than Alzheimer’s, but in combination, it makes Alzheimer’s symptoms worse, scientists say.

Published: December 1, 2025, 1:38 pm

Paul Ekman, Who Linked Facial Expressions to Universal Emotions, Dies at 91

Often called the world’s most famous face reader, he inspired the TV show ‘Lie to Me.’ But some questioned his assumption that human expressions were ‘pan-cultural.’

Published: December 1, 2025, 8:55 pm

‘It’s going much too fast’: the inside story of the race to create the ultimate AI

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In Silicon Valley, rival companies are spending trillions of dollars to reach a goal that could change humanity – or potentially destroy it

On the 8.49am train through Silicon Valley, the tables are packed with young people glued to laptops, earbuds in, rattling out code.

As the northern California hills scroll past, instructions flash up on screens from bosses: fix this bug; add new script. There is no time to enjoy the view. These commuters are foot soldiers in the global race towards artificial general intelligence – when AI systems become as or more capable than highly qualified humans.

Continue reading...

Published: December 1, 2025, 10:00 am

‘It was extremely pornographic’: Cara Hunter on the deepfake video that nearly ended her political career

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The Irish politician was targeted in 2022, in the final weeks of her run for office. She has never found out who made the malicious deepfake, but knew immediately she had to try to stop this happening to other women

When Cara Hunter, the Irish politician, looks back on the moment she found out she had been deepfaked, she says it is “like watching a horror movie”. The setting is her grandmother’s rural home in the west of Tyrone on her 90th birthday, April 2022. “Everyone was there,” she says. “I was sitting with all my closest family members and family friends when I got a notification through Facebook Messenger.” It was from a stranger. “Is that you in the video … the one going round on WhatsApp?” he asked.

Hunter made videos all the time, especially then, less than three weeks before elections for the Northern Ireland assembly. She was defending her East Londonderry seat, campaigning, canvassing, debating. Yet, as a woman, this message from a man she didn’t know was enough to put her on alert. “I replied that I wasn’t sure which video he was talking about,” Hunter says. “So he asked, did I want to see it?” Then he sent it over.

Continue reading...

Published: December 1, 2025, 5:00 am

James Cameron says AI actors are ‘horrifying to me’

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Avatar director, known for his advocacy of new technology, told interviewer generative AI performance puts ‘all human experience into a blender’

Avatar director James Cameron has called AI actors “horrifying” and said what generative AI technology creates is “an average”.

Cameron was speaking to CBS on Sunday Morning in the run-up to the release of the third Avatar film, subtitled Fire and Ash, and was asked about the pioneering technology he used in his film-making. After praising motion-capture performance as “a celebration of the actor-director moment”, Cameron expressed his disdain for artificial intelligence. “Go to the other end of the spectrum [from motion capture] and you’ve got generative AI, where they can make up a character. They can make up an actor. They can make up a performance from scratch with a text prompt. It’s like, no. That’s horrifying to me. That’s the opposite. That’s exactly what we’re not doing.”

Continue reading...

Published: December 1, 2025, 2:21 pm

‘The Chinese will not pause’: Volvo and Polestar bosses urge EU to stick to 2035 petrol car ban

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Exclusive: Swedish carmakers push to retain target as Germany lobbies to help its own industry by softening cutoff date

As the battle lines harden amid Germany’s intensifying pressure on the European Commission to scrap the 2035 ban on production of new petrol and diesel cars, two Swedish car companies, Volvo and Polestar, are leading the campaign to persuade Brussels to stick to the date.

They argue such a move is a desperate attempt to paper over the cracks in the German car industry, adding that it will not just prolong take up of electric vehicles but inadvertently hand the advantage to China.

Continue reading...

Published: December 2, 2025, 6:00 am

The 110 very best Cyber Monday deals in the US, curated and vetted

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Our experts found the best deals and sales that are actually worth your money. Here are our picks for pillows, bath towels, suitcases and more

The Guardian’s journalism is independent. We will earn a commission if you buy something through an affiliate link. Learn more.

We all have holiday traditions we look forward to each year: cooking your grandmother’s classic stuffing recipe. Opening your favorite Advent calendar. Or, if you’re a retailer, pushing deals for Black Friday and Cyber Monday.

JUST ADDED: The best Cyber Monday streaming deal:
Disney+ and Hulu bundle for 12 months

Continue reading...

Published: December 1, 2025, 9:39 pm

The 33+ best US Cyber Monday travel deals on luggage, backpacks, travel adapters and more

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From Away, Calpak and Samsonite, here are budget-friendly reasons to upgrade your luggage, replace your headphones and upgrade your travel photos

While the Cyber Monday deals landscape can be overwhelming – and you might be tempted to avoid it completely – some actually incredible deals do exist out there, particularly in the travel space. As a travel journalist and the writer of a packing list newsletter, I’m always on the hunt for luggage, clothing and gear that will streamline my travel process. During Black Friday and Cyber Monday sales, I keep a trained eye on the retailers with genuine discounts on carry-on suitcases, comfortable loungewear and more. Pro tip: if a specific item catches my eye, I will Google it to see if another website is offering a more enticing deal. (It usually is.)

So if you’re hunting for items that will upgrade your travels without blowing your budget, use my curated guide to inform your shopping.

The best luggage deal:
Away Packing Pro Bundle

Continue reading...

Published: December 1, 2025, 8:51 pm

The 28 gifts and treats Filter US writers are loving this holiday season

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From durable Converse dupes to laundry detergent sheets, our product reviewers reveal what products earned spots in their daily lives

At the Filter US, our writers test plenty of things in the line of duty: bath towels, sleep masks, AirPods Pro, blenders, toaster ovens, instant coffee and more. So what are they putting in their own shopping carts?

This holiday season, the Filter team asked our product reviewers to share what they’re personally using and loving. Their answers ran the gamut: a portable projector that transforms any wall into a private theater, a more durable dupe of Converse’s Chuck Taylors, a trigger-point massage tool to loosen tight muscles and laundry detergent sheets that are kind to the planet and easy to use, to name a few. Read on for the 28 most loved items that earned a spot in our writers’ daily lives. Karen Yuan, Filter US commissioning editor

Continue reading...

Published: December 1, 2025, 8:15 pm

The question isn’t whether the AI bubble will burst – but what the fallout will be

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Will the bubble ravage the economy when it bursts? What will it leave of value once it pops?

The California Gold Rush left an outsized imprint on America. Some 300,000 people flocked there from 1848 to 1855, from as far away as the Ottoman Empire. Prospectors massacred Indigenous people to take the gold from their lands in the Sierra Nevada mountains. And they boosted the economies of nearby states and faraway countries from whence they bought their supplies.

Gold provided the motivation for California – a former Mexican territory then controlled by the US military – to become a state with laws of its own. And yet, few “49ers” as prospectors were known, struck it rich. It was the merchants selling prospectors food and shovels who made the money. One, a Bavarian immigrant named Levi Strauss who sold denim overalls to the gold bugs passing through San Francisco, may be the most remembered figure of his day.

Continue reading...

Published: December 1, 2025, 11:00 am

Age of the ‘scam state’: how an illicit, multibillion-dollar industry has taken root in south-east Asia

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Like the narco-state, a ‘scam state’ refers to countries where an illicit industry has dug its tentacles deep into institutions and transformed the economy

For days before the explosions began, the business park had been emptying out. When the bombs went off, they took down empty office blocks and demolished echoing, multi-cuisine food halls. Dynamite toppled a four-storey hospital, silent karaoke complexes, deserted gyms and dorm rooms.

So came the end of KK Park, one of south-east Asia’s most infamous “scam centres”, press releases from Myanmar’s junta declared. The facility had held tens of thousands of people, forced to relentlessly defraud people around the world. Now, it was being levelled piece by piece.

Continue reading...

Published: December 2, 2025, 2:02 am

Shortage of ‘breakthrough’ weight loss drugs will slow fight against obesity, WHO warns

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WHO urges countries to make drugs such as Mounjaro more accessible to people and asks drugs companies to lower prices

Weight loss drugs such as Mounjaro offer huge potential to tackle soaring obesity globally but are currently only available to one in 10 of those who need them, the World Health Organization has said.

Their proven effectiveness in helping people lose weight means the medications represent “a new chapter” in how health services can treat obesity and the killer diseases it causes, the WHO added.

Continue reading...

Published: December 1, 2025, 1:45 pm

NHS to pay 25% more for innovative drugs after UK–US zero-tariff deal

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Agreement could cost NHS an extra £3bn a year, industry sources estimate

The UK has agreed to pay 25% more for new medicines by 2035 as part of a US-UK drug pricing deal that will cost an estimated additional £3bn a year.

The transatlantic agreement will also see the health service in England, which currently spends £14.4bn a year on innovative therapies, double the percentage of GDP it allocates to buying such products, from 0.3% to 0.6% over the next decade.

Continue reading...

Published: December 1, 2025, 6:26 pm

Starwatch: Mercury offers rare viewing chance for early risers

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Elusive planet will make a pre-dawn appearance as it seems to stray from the sun

We start December with one of the best chances to see Mercury this year, at least for the northern hemisphere. The elusive inner planet never strays far from the sun but this week it reaches the configuration known as the greatest western elongation.

This means that from our vantage point on Earth, the planet appears as far away as possible from the sun. It will appear in the pre-dawn twilight sky. For observers at mid-northern latitudes, the geometry is favourable, and so the best views are possible 30 to 60 minutes before sunrise.

Continue reading...

Published: December 1, 2025, 6:00 am

Tuesday briefing: What’s next for the resurgent space race?

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In today’s newsletter: As suppliers get ready to meet policy makers and space agencies at the industry’s largest gathering, a look at the exploration and exploitation of space

Good morning. This week Glasgow hosts one of the UK’s largest ever gatherings of the space industry at Space-Comm. With representatives of Nasa, the UK and Scottish governments and the UK space agency among 2,000 space leaders gathering there, it is a chance for people in the commercial supply chain of the space exploration industry to meet policy makers and space agencies.

It comes at a crucial moment in the exploration – and exploitation – of space. For almost three decades the International Space Station (ISS) has bound the US and Russia into cooperation and shared interests. That project is nearing its end, and we can expect to see a realignment of missions and goals – which may bring states and scientists into conflict.

Politics | Britain’s budget watchdog, the Office for Budget Responsibility, has said the early leak of its budget documents before Rachel Reeves made her speech last week, was the “worst failure” in its 15-year history, as its chair resigned and it emerged a similar leak had happened earlier this year.

Health | The World Health Organization has urged countries to make weight loss drugs more accessible and pharmaceutical companies to lower their prices, saying jabs including Mounjaro represent a “new chapter” in the fight against obesity.

Ukraine | The coming days may be “pivotal” for talks to end the war in Ukraine, the EU’s top diplomat said, as Volodymyr Zelenskyy met Emmanuel Macron in Paris on Monday and the US envoy Steve Witkoff flew out to meet Vladimir Putin in Moscow on Tuesday.

Donald Trump | Donald Trump said he “wouldn’t have wanted” a second strike that the US military reportedly conducted on a boat in the Caribbean that it believed to be ferrying drugs, killing survivors of an initial missile attack. The UN human rights chief, Volker Türk, has urged Washington to investigate, saying there was “strong evidence” of “extrajudicial” killings.

Asia-Pacific | Sri Lanka and Indonesia have deployed military personnel to help victims of the torrential floods that have killed 1,100 in four countries in Asia. Heavy cyclones and tropical monsoon rains have hit the region in recent days.

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Published: December 2, 2025, 6:40 am

Hole in Antarctic ozone layer shrinks to smallest since 2019, scientists say

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EU’s Copernicus monitoring service hails ‘reassuring sign’ of progress observed this year in hole’s size and duration

The hole in the ozone layer over the Antarctic this year was the smallest and shortest-lived since 2019, according to European space scientists, who described the finding as a “reassuring sign” of the layer’s recovery.

The yearly gap in what scientists have called “planetary sunscreen” reached a maximum area of 21m sq km (8.1m sq miles) over the southern hemisphere in September – well below the maximum of 26m sq km reached in 2023 – and shrank in size until coming to an early close on Monday, data from the Copernicus Atmosphere Monitoring Service (Cams) shows.

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Published: December 1, 2025, 3:53 pm

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