Is it true that … you’re more likely to get sick when you’re stressed?

Stress releases hormones such as adrenaline and cortisol, which can suppress your immune system – but chronic concerns are more of an issue than short-term worries

‘Stress has a well-established effect on your immune health,” says Daniel M Davis, head of life sciences at Imperial College London. “But stress is a very broad phenomenon. You can feel stressed watching a horror movie, or you can experience long-term stress, like going through a divorce.”

Short-term stress can temporarily affect your immune system. “The number of immune cells in the blood changes,” says Davis. “But it returns to normal within about an hour, so it’s unlikely to have any major impact.”

Published: December 29, 2025, 8:00 am

‘This will be a stressful job’: Sam Altman offers $555k salary to fill most daunting role in AI

New head of preparedness at OpenAI will face unnerving in-tray amid fears from some experts that AI could ‘turn on us’

The maker of ChatGPT has advertised a $555,000-a-year vacancy with a daunting job description that would cause Superman to take a sharp intake of breath.

In what may be close to the impossible job, the “head of preparedness” at OpenAI will be directly responsible for defending against risks from ever more powerful AIs to human mental health, cybersecurity and biological weapons.

Published: December 29, 2025, 2:44 pm

‘Why should we pay these criminals?’: the hidden world of ransomware negotiations

Cybersecurity experts reveal what they do for high-profile clients targeted by hackers such as Scattered Spider

They call it “stopping the bleeding”: the vital window to prevent an entire database from being ransacked by criminals or a production line grinding to a halt.

When a call comes into the cybersecurity firm S-RM, headquartered on Whitechapel High Street in east London, a hacked business or institution may have just minutes to protect themselves.

Published: December 29, 2025, 1:38 pm

UK accounting body to halt remote exams amid AI cheating

Candidates will have to sit assessments in person unless there are exceptional circumstances, says ACCA

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The world’s largest accounting body is to stop students being allowed to take exams remotely to crack down on a rise in cheating on tests that underpin professional qualifications.

The Association of Chartered Certified Accountants (ACCA), which has almost 260,000 members, has said that from March it will stop allowing students to take online exams in all but exceptional circumstances.

Published: December 29, 2025, 8:19 am

SoftBank to acquire DigitalBridge for $4bn in move to deepen ties to AI

Acquisition would further expand SoftBank’s investments in artificial intelligence as it tries to center itself in the boom

SoftBank Group will acquire digital infrastructure investor DigitalBridge Group in a deal valued at $4bn, the companies said on Monday, as the Japanese investment firm looks to deepen its AI-related portfolio.

The acquisition would expand SoftBank’s exposure to digital infrastructure as the Japanese conglomerate is positioning its portfolio to focus on artificial intelligence.

SoftBank’s billionaire founder Masayoshi Son is seeking to capitalize on surging demand for the computing capacity that underpins artificial intelligence applications.

Published: December 29, 2025, 3:05 pm

Arc Raiders review – pure multiplayer pleasure

PC, Xbox, PlayStation 5; Embark Studios
The breakout hit, which has players coming together (or turning on each other) to battle intimidating robots in an apocalyptic future, is worth the hype

Arc Raiders is an extraction shooter from Embark Studios – so, a game where you deploy into a map full of other players and do as much shooting and looting as you can before making an escape. This is my first real go at the genre, and it’s excellent. It has smooth, only occasionally cumbersome combat, sound design that scratches the brain just right and robotic enemies that genuinely terrify. And it satisfies my constant need to sift through my inventory and rifle through every drawer.

But I have to keep my head on a swivel: Arc Raider’s player v player element means I can get jumped for my precious cargo by a malicious rival at any moment. And also, the knowledge that this game was made with the help of generative AI voice acting makes me slightly ashamed of how much I enjoy it. I play every game sheepishly looking over my shoulder (and my character’s) in case someone in-game takes my sought-after blueprint, or someone in real life kicks down my door to call me a hypocrite.

Published: December 29, 2025, 10:00 am

More than 300 earthquakes recorded in UK this year, study finds

Western Highlands and southern Wales among most active regions, according to British Geological Survey

More than 300 earthquakes have been recorded in the UK this year, according to the British Geological Survey (BGS).

Among the most active regions to experience quakes were Perthshire and the western Highlands in Scotland, southern parts of Wales, and Yorkshire and Lancashire in England, the BGS data shows.

Published: December 29, 2025, 5:00 am

Starwatch: tracking down Aries, the faint ram of winter skies

One of the zodiac’s subtler constellations comes into view on winter evenings, with the moon helping to point the way

You can track down one of the zodiac’s fainter constellations this week. Aries, the ram, lies between Taurus to the east and Pisces to the west. In the northern hemisphere, it is situated at its best during the deep winter months.

Aries is an ancient constellation. It was originally designated by the early Babylonians as a hired hand who tended fields, but became recognised as a ram and has remained so in most sky cultures. To the Egyptians, it was Amun-Ra, the ram-headed god of creativity and fertility. In Greek myth, Aries is associated with the golden fleece that Jason and the Argonauts sought.

Published: December 29, 2025, 6:00 am

UK medical regulator warns against buying weight-loss jabs from social media channels

MHRA says buying from illegal online sellers can put health at real risk amid booming black market

Losing weight may be a common new year resolution but health experts have warned against buying medications for such purposes from social media sellers or other illegitimate channels.

Jabs such as Wegovy and Mounjaro have become hugely popular for weight loss, with trials suggesting the latter can help people lose an average of 20% of their body weight after 72 weeks of treatment.

Published: December 29, 2025, 1:53 pm

The Guardian view on antibiotics: recent breakthroughs are great news, but humanity is losing the bigger race | Editorial

Our magic bullets are increasingly rare and ineffective. The golden age of discovery is over and the way we develop and use drugs needs to change

During her tenure as director general of the World Health Organization, Dr Margaret Chan used to say that all of the “easy” antibiotics had already been found. Her point was that in responding to the urgent threat of antibiotic-resistant infections, we would struggle to find new medicines – or preserve the ones we have – if we didn’t find new ways of working. She was right.

Since 2017, just 16 antibiotics have gained widespread regulatory approval – mostly close relatives of medicines already in use and so unlikely to evade resistance for long. The development of new ones is a slow and unprofitable business, curative medicines being less lucrative than ones treating longer-term conditions. And the scientific outlook remains bleak.

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Published: December 29, 2025, 6:30 pm